1 00:00:08,749 --> 00:00:05,900 many experiments on the International 2 00:00:10,280 --> 00:00:08,759 Space Station are intended to learn what 3 00:00:11,720 --> 00:00:10,290 we can about the conditions of long-term 4 00:00:13,669 --> 00:00:11,730 space flight as a part of the 5 00:00:15,589 --> 00:00:13,679 preparations for future missions out 6 00:00:17,420 --> 00:00:15,599 into the solar system that includes 7 00:00:19,790 --> 00:00:17,430 experiments that use the human crew 8 00:00:21,950 --> 00:00:19,800 members as test subjects and those that 9 00:00:23,839 --> 00:00:21,960 focus on the millions of other living 10 00:00:25,910 --> 00:00:23,849 things on the station that microbes 11 00:00:28,009 --> 00:00:25,920 which share the station environment with 12 00:00:29,689 --> 00:00:28,019 the human crew commander Terry Virts 13 00:00:31,669 --> 00:00:29,699 will be taking samples for the 14 00:00:33,920 --> 00:00:31,679 experiment microbial Observatory 15 00:00:36,920 --> 00:00:33,930 tomorrow and today were joined by the 16 00:00:39,440 --> 00:00:36,930 principal investigator dr. Koster E van 17 00:00:41,650 --> 00:00:39,450 Casa Juan of the California Institute of 18 00:00:44,060 --> 00:00:41,660 Technology and the Jet Propulsion 19 00:00:46,820 --> 00:00:44,070 Laboratory in Pasadena California to 20 00:00:48,400 --> 00:00:46,830 learn more about it hi dr. VIN qotsa 21 00:00:51,410 --> 00:00:48,410 Juan thank you for joining us today 22 00:00:52,220 --> 00:00:51,420 hi how are you thank you for having us 23 00:00:54,170 --> 00:00:52,230 under there 24 00:00:56,110 --> 00:00:54,180 thank you we really appreciate you 25 00:00:57,770 --> 00:00:56,120 joining us to talk about some about this 26 00:01:01,130 --> 00:00:57,780 experiment that they're going to be 27 00:01:02,300 --> 00:01:01,140 working on I know today Terry is 28 00:01:04,039 --> 00:01:02,310 actually reviewing some of the 29 00:01:06,590 --> 00:01:04,049 procedures for that and now he'll begin 30 00:01:08,780 --> 00:01:06,600 doing some of the samples tomorrow so 31 00:01:10,070 --> 00:01:08,790 let's suppose just talk about where do 32 00:01:13,070 --> 00:01:10,080 the microbes on the space station 33 00:01:15,490 --> 00:01:13,080 where are they um they're everywhere 34 00:01:18,410 --> 00:01:15,500 like you know we breathe and then we 35 00:01:22,100 --> 00:01:18,420 inhale and exhale microbes every day I 36 00:01:24,230 --> 00:01:22,110 like you know so International Space 37 00:01:25,460 --> 00:01:24,240 Station is not a in our different 38 00:01:29,020 --> 00:01:25,470 environment a that other than 39 00:01:31,880 --> 00:01:29,030 microgravity so so they are everywhere 40 00:01:33,970 --> 00:01:31,890 we have to look for it and where did 41 00:01:37,730 --> 00:01:33,980 that come from 42 00:01:39,500 --> 00:01:37,740 yeah that's a great question so normally 43 00:01:40,820 --> 00:01:39,510 people say that it comes you know when 44 00:01:43,580 --> 00:01:40,830 you are living in your house the 45 00:01:45,260 --> 00:01:43,590 microbes comes from outside but in the 46 00:01:46,940 --> 00:01:45,270 case of the International Space Station 47 00:01:49,610 --> 00:01:46,950 you don't have a football outside 48 00:01:52,190 --> 00:01:49,620 football field so the dad comes in and 49 00:01:55,610 --> 00:01:52,200 now but actually the human are the 50 00:01:58,310 --> 00:01:55,620 walking fermenters so they hold say 10 51 00:01:59,920 --> 00:01:58,320 to the 14 cells microbial cells when 52 00:02:03,010 --> 00:01:59,930 compared to their 53 00:02:06,550 --> 00:02:03,020 on a career Accel's they are about 54 00:02:09,249 --> 00:02:06,560 thousand times more and it might come 55 00:02:12,160 --> 00:02:09,259 from the earth through the cargo and the 56 00:02:15,340 --> 00:02:12,170 human who are traveling between them so 57 00:02:18,040 --> 00:02:15,350 the main sores are human as well as the 58 00:02:22,030 --> 00:02:18,050 cut the stuff comes from the earth as a 59 00:02:24,090 --> 00:02:22,040 cargo okay thank you so if we can't 60 00:02:27,340 --> 00:02:24,100 control the microbes that are present 61 00:02:31,690 --> 00:02:27,350 why is it important that we identify and 62 00:02:35,260 --> 00:02:31,700 monitor the microbes it is not it is not 63 00:02:37,960 --> 00:02:35,270 that we cannot control the thing is it 64 00:02:39,699 --> 00:02:37,970 is different from what we are seeing in 65 00:02:42,880 --> 00:02:39,709 the earth compared to what is in a 66 00:02:45,699 --> 00:02:42,890 closed environment because NASA has 67 00:02:49,210 --> 00:02:45,709 taken at most care to have appropriate 68 00:02:51,510 --> 00:02:49,220 and air environmental system of a closed 69 00:02:55,390 --> 00:02:51,520 system like in space stations to see 70 00:02:57,760 --> 00:02:55,400 what can be there in the air in the air 71 00:02:59,530 --> 00:02:57,770 of the space station which is a very 72 00:03:01,780 --> 00:02:59,540 closed system where you know a lot of 73 00:03:05,080 --> 00:03:01,790 things are being inhale inhale and 74 00:03:08,080 --> 00:03:05,090 exhale by the human present in there so 75 00:03:10,930 --> 00:03:08,090 it is not that you cannot control but 76 00:03:14,259 --> 00:03:10,940 you need to know what is in there 77 00:03:16,750 --> 00:03:14,269 so that for a long period of human 78 00:03:19,479 --> 00:03:16,760 habitation in a closed system you can 79 00:03:22,780 --> 00:03:19,489 learn from there and a wide there kind 80 00:03:25,030 --> 00:03:22,790 of prevention so that if you monitor 81 00:03:27,910 --> 00:03:25,040 what is in there you can prevent easily 82 00:03:30,310 --> 00:03:27,920 and we should not forget the microbes 83 00:03:32,050 --> 00:03:30,320 are integral part of the human so there 84 00:03:35,199 --> 00:03:32,060 are a lot of beneficial microbes out 85 00:03:37,600 --> 00:03:35,209 there that helps us also we are not 86 00:03:39,820 --> 00:03:37,610 living in a sterile and ramen okay we 87 00:03:42,550 --> 00:03:39,830 are not transgenic human what that means 88 00:03:44,560 --> 00:03:42,560 is we are not made up of one single 89 00:03:48,910 --> 00:03:44,570 thing we are made up of multiple things 90 00:03:51,340 --> 00:03:48,920 so human knows how to live with things 91 00:03:52,990 --> 00:03:51,350 together a kind of immune system they 92 00:03:56,680 --> 00:03:53,000 are developed so that you know for some 93 00:03:59,710 --> 00:03:56,690 other unwanted thing they can fight the 94 00:04:02,130 --> 00:03:59,720 microbes out there can fight from other 95 00:04:06,670 --> 00:04:02,140 bad microbes also so basically 96 00:04:10,390 --> 00:04:06,680 maintenance is a key part to live and 97 00:04:11,960 --> 00:04:10,400 have a better living conditions in a 98 00:04:13,970 --> 00:04:11,970 closed system 99 00:04:16,580 --> 00:04:13,980 okay thank you so much for that 100 00:04:18,229 --> 00:04:16,590 information so I know Terry is gonna be 101 00:04:20,360 --> 00:04:18,239 gathering samples tomorrow can you 102 00:04:23,240 --> 00:04:20,370 describe for me the on-orbit part of 103 00:04:24,650 --> 00:04:23,250 this this experiment how and where are 104 00:04:28,910 --> 00:04:24,660 they going to be gathering or where will 105 00:04:30,170 --> 00:04:28,920 he be gathering the samples I think you 106 00:04:33,100 --> 00:04:30,180 might have shown some of the places 107 00:04:36,290 --> 00:04:33,110 where we are collecting samples so we 108 00:04:39,560 --> 00:04:36,300 have ordered this experiment through 109 00:04:41,780 --> 00:04:39,570 NASA space biology program to use the 110 00:04:45,470 --> 00:04:41,790 state-of-the-art molecular techniques to 111 00:04:49,570 --> 00:04:45,480 see how the microbes are you know 112 00:04:52,640 --> 00:04:49,580 they're in setup locations for example 113 00:04:55,280 --> 00:04:52,650 astronauts are using the exercise 114 00:04:57,890 --> 00:04:55,290 platform so they sweat a lot so that 115 00:05:00,770 --> 00:04:57,900 means they also you know shed a lot of 116 00:05:03,920 --> 00:05:00,780 microbes so that kind of places where a 117 00:05:07,280 --> 00:05:03,930 lot of activity is going on are the main 118 00:05:09,130 --> 00:05:07,290 target does have and also day-to-day 119 00:05:11,840 --> 00:05:09,140 they have to eat so there are certain 120 00:05:14,510 --> 00:05:11,850 specified area where they can eat and 121 00:05:17,510 --> 00:05:14,520 then you know chat so that is the other 122 00:05:20,690 --> 00:05:17,520 place where people can you know shed 123 00:05:22,850 --> 00:05:20,700 stuff so a dining table and this 124 00:05:25,730 --> 00:05:22,860 particular experiment is on the es side 125 00:05:28,850 --> 00:05:25,740 only so we are having the nodes 1 & 2 & 126 00:05:31,070 --> 00:05:28,860 3 are covered of the aside as well as 127 00:05:34,040 --> 00:05:31,080 some of the exercise place and we also 128 00:05:36,920 --> 00:05:34,050 have other experiments which around the 129 00:05:39,170 --> 00:05:36,930 way to collaborate with the European and 130 00:05:44,060 --> 00:05:39,180 Japanese people to measure the microbial 131 00:05:49,080 --> 00:05:44,070 diversity of there's you know section of 132 00:05:55,210 --> 00:05:53,140 okay so so now we know where and I think 133 00:05:57,550 --> 00:05:55,220 you've also described also you know why 134 00:05:59,490 --> 00:05:57,560 you chose these locations the samples 135 00:06:01,450 --> 00:05:59,500 are being returned on Dragon will you be 136 00:06:06,130 --> 00:06:01,460 analyzing these or how do you analyze 137 00:06:09,970 --> 00:06:06,140 the samples yeah so for the past two 138 00:06:12,220 --> 00:06:09,980 10-15 years NASA is monitoring based on 139 00:06:14,440 --> 00:06:12,230 the traditional culture based analysis 140 00:06:16,930 --> 00:06:14,450 so we all know that you know you can get 141 00:06:18,150 --> 00:06:16,940 only one to ten percent of information 142 00:06:21,160 --> 00:06:18,160 if you are using the traditional 143 00:06:23,770 --> 00:06:21,170 microbiological methods so this state of 144 00:06:26,410 --> 00:06:23,780 the art has evolved from traditional 145 00:06:29,860 --> 00:06:26,420 microbiology using the genomic analysis 146 00:06:31,870 --> 00:06:29,870 so we are using the gene based system to 147 00:06:34,270 --> 00:06:31,880 get the genetic fingerprinting of these 148 00:06:37,570 --> 00:06:34,280 things so that would help us to see 149 00:06:39,520 --> 00:06:37,580 whether any particular cargo is taking a 150 00:06:41,860 --> 00:06:39,530 particular kind of microbes all the time 151 00:06:44,650 --> 00:06:41,870 so you have to repeat again and again 152 00:06:47,860 --> 00:06:44,660 the same sort of method methods so that 153 00:06:50,440 --> 00:06:47,870 you understand where to Minar control 154 00:06:52,300 --> 00:06:50,450 and mitigate the plan so the 155 00:06:55,030 --> 00:06:52,310 state-of-the-art molecular technologies 156 00:06:57,430 --> 00:06:55,040 are very powerful and not time-consuming 157 00:06:59,440 --> 00:06:57,440 and also not laborious and also analyzed 158 00:07:03,100 --> 00:06:59,450 a lot more samples so we are using 159 00:07:05,430 --> 00:07:03,110 molecular techniques right and how do 160 00:07:08,680 --> 00:07:05,440 you anticipate on using the results of 161 00:07:14,440 --> 00:07:08,690 this study I mean on-orbit and also on 162 00:07:16,450 --> 00:07:14,450 earth correct so there are a couple of 163 00:07:18,040 --> 00:07:16,460 things that number one is you know if 164 00:07:21,130 --> 00:07:18,050 you know what are the things out there 165 00:07:24,730 --> 00:07:21,140 whether that is beneficial to humankind 166 00:07:26,500 --> 00:07:24,740 are the one that is not good and harmful 167 00:07:29,100 --> 00:07:26,510 and you know sometimes under 168 00:07:32,080 --> 00:07:29,110 microgravity some changes might happen 169 00:07:34,810 --> 00:07:32,090 if such kind of mutate mutation is 170 00:07:37,450 --> 00:07:34,820 happening then you will know what needs 171 00:07:40,240 --> 00:07:37,460 to be targeted and eradicated using 172 00:07:42,580 --> 00:07:40,250 appropriate cleaning regimes as well as 173 00:07:45,940 --> 00:07:42,590 some sort of mitigation plants can 174 00:07:49,030 --> 00:07:45,950 happen so this is the first step towards 175 00:07:51,850 --> 00:07:49,040 you know achieving that particular goal 176 00:07:53,590 --> 00:07:51,860 how to maintain a better living 177 00:07:55,870 --> 00:07:53,600 condition for the astronauts for a 178 00:07:58,870 --> 00:07:55,880 longer period of time so right now we 179 00:08:00,910 --> 00:07:58,880 are getting data for two to three years 180 00:08:05,280 --> 00:08:00,920 and that can be you 181 00:08:07,920 --> 00:08:05,290 to suggest NASA how to build appropriate 182 00:08:11,800 --> 00:08:07,930 Andromeda control system thereby 183 00:08:14,380 --> 00:08:11,810 containing certain microbial parameters 184 00:08:16,300 --> 00:08:14,390 and also as it said all the time there 185 00:08:19,510 --> 00:08:16,310 are certain many beneficial microbes out 186 00:08:22,450 --> 00:08:19,520 there that helps us to produce it for 187 00:08:23,980 --> 00:08:22,460 tomorrow's food processing for example 188 00:08:27,250 --> 00:08:23,990 if you are going to have a human 189 00:08:29,260 --> 00:08:27,260 presence in you know faraway planets you 190 00:08:31,960 --> 00:08:29,270 know the one of the biggest thing is how 191 00:08:33,670 --> 00:08:31,970 do you keep the food and replenish it so 192 00:08:36,820 --> 00:08:33,680 some of the beneficial microbes that 193 00:08:39,490 --> 00:08:36,830 you'll see there might be useful to the 194 00:08:41,710 --> 00:08:39,500 conditions that helps them to process 195 00:08:45,670 --> 00:08:41,720 such kind of things and then get 196 00:08:47,980 --> 00:08:45,680 benefited well thank you very much for 197 00:08:49,870 --> 00:08:47,990 joining me again dr. Pincus Juan it's 198 00:08:51,340 --> 00:08:49,880 very interesting research and we look 199 00:08:52,810 --> 00:08:51,350 forward to learning more about the 200 00:08:56,410 --> 00:08:52,820 findings that you have throughout this 201 00:08:58,780 --> 00:08:56,420 thank you very much you're very welcome 202 00:09:01,150 --> 00:08:58,790 and a special thanks to the commander of